PřF:C9531 Structure of biomacromolecules - Course Information
C9531 Structure of biomacromolecules
Faculty of ScienceAutumn 2004
- Extent and Intensity
- 0/1/0. 1 credit(s) (fasci plus compl plus > 4). Type of Completion: z (credit).
- Teacher(s)
- prof. Mgr. Lukáš Žídek, Ph.D. (seminar tutor)
- Guaranteed by
- prof. Mgr. Lukáš Žídek, Ph.D.
Chemistry Section – Faculty of Science
Contact Person: prof. Mgr. Lukáš Žídek, Ph.D. - Timetable
- Tue 11:00–11:50 Cpm,02016
- Prerequisites
- NOW( c9530 Structure of biomacromolecules )
The seminar is offered to students attending course C9530 (Structure of biomacromolecules). - Course Enrolment Limitations
- The course is also offered to the students of the fields other than those the course is directly associated with.
- fields of study / plans the course is directly associated with
- Applied Biochemistry (programme PřF, B-AB)
- Applied Biochemistry (programme PřF, B-CH)
- Biochemistry (programme PřF, M-CH)
- Course objectives
- The aim of the seminar is to offer the chance to practice the knowledge acquired in course C9530 (Structure of biomacromolecules) and to prepare students for the exam of the course C9530.
- Syllabus
- 1. Structure of macromolecules, basic structural motifs of proteins and nucleic acids, structure of saccharides and membranes. 2. General characterization of proteins, methods of optical and mass spectroscopy, protein sequencing. 3. Nucleic acid sequencing, techniques of gene engineering, expression of recombinant proteins. 4-6. X-ray crystallography. Crystal preparation, diffraction experiment, methods of solving phase problem, electron density maps, structure model building. 7-9. Nuclear magnetic resonance. Isotope labeling, NMR experiment, spectral frequency assignment, determination of geometry (NOE, coupling constants), protein dynamics. 10-11. Molecular mechanics and dynamics, simulated annealing, experimental restraints. 12. Databases of structures, bioinformatics, computer prediction and modeling.
- Language of instruction
- Czech
- Further Comments
- The course is taught annually.
- Teacher's information
- http://www.ncbr.chemi.muni.cz/~lzidek/C9531.html
- Enrolment Statistics (Autumn 2004, recent)
- Permalink: https://is.muni.cz/course/sci/autumn2004/C9531