PřF:Bi9260 Cell mol neurobiology - Course Information
Bi9260 Cellular and molecular neurobiology
Faculty of ScienceSpring 2009
- Extent and Intensity
- 2/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
- Teacher(s)
- prof. Mgr. Petr Beneš, Ph.D. (lecturer)
- Guaranteed by
- prof. RNDr. Jan Šmarda, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. Mgr. Petr Beneš, Ph.D. - Timetable
- Tue 13:00–14:50 C03/117
- Prerequisites
- Bi4020 Molecular biology && Bi7090 Eukaryotic cells
Principal knowledge of physiology, cell and molecular biology with focus on eukaryotic organisms. - Course Enrolment Limitations
- The course is also offered to the students of the fields other than those the course is directly associated with.
- fields of study / plans the course is directly associated with
- Molecular and Cellular Biology (programme PřF, D-BI4)
- Molecular Biology and Genetics (programme PřF, N-BI)
- General and Molecular Genetics (programme PřF, D-BI4)
- Course objectives
- This course provides essential informations about the development and function of nervous system with emphasis on integration of modern approaches of physiology and molecular biology. The main objectives of the course are the following: neuronal cell growth, differentiation, neuronal cell death, cell signaling and specific functions of neuronal cells. Essential and recent informations about basic principles of learning, memory and behaviour are also discussed.
- Syllabus
- Use of model organisms for functional and developmental studies of nervous system (Drosophila, Xenopus, Aplysia, C. elegans, Mus musculus, tissue culture). Neurons and neuroglial cells - morphology, function, mutual interaction. Neuron signals - electrical activity, excitability, ion channels, synapses, neurotransmitters, neuromodulators, neuropeptides. Cell signaling in nervous system - G-protein coupled receptors, cAMP, calcium signaling, protein phosphorylation and dephosphorylation. Nervous system development, neural stem cells, differentiation of neurons and glia, specific regulation of gene expression. Brain development - homeiotic genes, axon growth, axon pathfinding, synapsis formation, neuronal motility. Neuronal plasticity, synaptic plasticity, neuronal adaptation. Biological basis of behaviour, biological clocks, emotion, pain, stress. Sensory system, learning, memory. Aging and death of neurons, neuronal regeneration, neuronal diseases, neuropharmacology.
- Literature
- Molecular biology of the neuron. Edited by R. Wayne Davies - B. J. Morris. 2nd ed. Oxford: Oxford University Press, 2006, xvii, 480. ISBN 0198509979. info
- SMITH, C. U. M. Elements of molecular neurobiology. 3rd ed. Chichester: John Wiley & Sons, 2002, xvi, 613. ISBN 0471560383. info
- NICHOLLS, John G. From neuron to brain. 4th ed. Sunderland, Mass.: Sinauer Associates, 2001, 1 sv. ISBN 0878934391. info
- Assessment methods
- Type of the course: lecture Type of examination: written test
- Language of instruction
- Czech
- Further Comments
- The course is taught annually.
- Enrolment Statistics (Spring 2009, recent)
- Permalink: https://is.muni.cz/course/sci/spring2009/Bi9260