PřF:Bi9260 Cell mol neurobiology - Course Information
Bi9260 Cellular and molecular neurobiology
Faculty of ScienceSpring 2011
- Extent and Intensity
- 2/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
- Teacher(s)
- prof. Mgr. Petr Beneš, Ph.D. (lecturer)
- Guaranteed by
- prof. RNDr. Jan Šmarda, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. Mgr. Petr Beneš, Ph.D. - Timetable
- Tue 8:00–9:50 B11/235
- Prerequisites
- Bi4020 Molecular biology && Bi7090 Eukaryotic cells
Principal knowledge of physiology, cell and molecular biology with focus on eukaryotic organisms. - Course Enrolment Limitations
- The course is also offered to the students of the fields other than those the course is directly associated with.
- fields of study / plans the course is directly associated with
- Molecular and Cellular Biology (programme PřF, D-BI4)
- Molecular Biology and Genetics (programme PřF, N-BI)
- General and Molecular Genetics (programme PřF, D-BI4)
- Course objectives
- At the end of this course students should be alble to understand essential principles of nervous system organisation, development and function. Students will be also able to explain key molecular mechanisms important for nervous system function.
- Syllabus
- Use of model organisms for functional and developmental studies of nervous system (Drosophila, Xenopus, Aplysia, C. elegans, Mus musculus, tissue culture). Neurons and neuroglial cells - morphology, function, mutual interaction. Neuron signals - electrical activity, excitability, ion channels, synapses, neurotransmitters, neuromodulators, neuropeptides. Cell signaling in nervous system - G-protein coupled receptors, cAMP, calcium signaling, protein phosphorylation and dephosphorylation. Nervous system development, neural stem cells, differentiation of neurons and glia, specific regulation of gene expression. Brain development - homeiotic genes, axon growth, axon pathfinding, synapsis formation, neuronal motility. Neuronal plasticity, synaptic plasticity, neuronal adaptation. Biological basis of behaviour, biological clocks, emotion, pain, stress. Sensory system, learning, memory. Aging and death of neurons, neuronal regeneration, neuronal diseases, neuropharmacology.
- Literature
- The neurobiology of learning and memory. Edited by J. W. Rudy. Sinauer Associates, 2008, 380 p. ISBN 978-0-87893-669-4
- Genetic dissection of neural circuits and behavior. Edited by S. F. Goodwin. Elsevier Inc., 2009, 199 p, ISBN 978-0-12-374836-2
- Molecular biology of the neuron. Edited by R. Wayne Davies - B. J. Morris. 2nd ed. Oxford: Oxford University Press, 2006, xvii, 480. ISBN 0198509979. info
- SMITH, C. U. M. Elements of molecular neurobiology. 3rd ed. Chichester: John Wiley & Sons, 2002, xvi, 613. ISBN 0471560383. info
- Teaching methods
- lectures, class discussion
- Assessment methods
- Type of examination: written test
- Language of instruction
- Czech
- Further Comments
- Study Materials
The course is taught annually.
- Enrolment Statistics (Spring 2011, recent)
- Permalink: https://is.muni.cz/course/sci/spring2011/Bi9260