VLBI0222p Biology II - lecture

Faculty of Medicine
Spring 2017
Extent and Intensity
1/0. 4 credit(s). Recommended Type of Completion: zk (examination). Other types of completion: RZk (examination).
Teacher(s)
Mgr. Kateřina Cetkovská, Ph.D. (lecturer)
prof. Ing. Petr Dvořák, CSc. (lecturer)
doc. Mgr. Lumír Krejčí, Ph.D. (lecturer)
RNDr. Pavel Krejčí, Ph.D. (lecturer)
Mgr. Vladimír Rotrekl, Ph.D. (lecturer)
prof. MUDr. Iva Slaninová, Ph.D. (lecturer)
prof. MUDr. David Šmajs, Ph.D. (lecturer)
RNDr. Mário Špírek, PhD. (lecturer)
Mgr. Bc. Stjepan Uldrijan, CSc. (lecturer)
Mgr. Kateřina Vopěnková, Ph.D. (lecturer)
Mgr. Kateřina Straková, Ph.D. (seminar tutor)
Jana Růžičková (assistant)
Mgr. Martina Vráblíková (assistant)
Guaranteed by
prof. Ing. Petr Dvořák, CSc.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: Mgr. Kateřina Cetkovská, Ph.D.
Supplier department: Department of Biology – Theoretical Departments – Faculty of Medicine
Timetable
Mon 7:30–8:20 B22/116 aula
Prerequisites
VLBI0121c Biology I -pract. && VLBI0121s Biology I - seminar
Knowledge of high-school biology and all previous lectures and practical classes of the subject are prerequisities for studying the course. Expected knowledge for each lecture is specified in the course syllabus. Literature recomended to study before each lecture is detailed in the interactive syllabus of the course.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
After completion of the course student: understands elementary cellular processes and processes taking place during development of a human body; comprehends the complexity of intercellular communication and mutual regulation of individual cells in a multicellular organism; knows basic principles of bacterial and viral diseases; is able to express basic coherence between malfunction in cellular processes and development of diseases, especially hereditary diseases, cancers or developmental defects, and understands the principle of genetic determination of hereditary diseases; can explain and justify action of some therapeutics with emphasis on modern medicine. Student is also able to apply this knowledge and skills in other subject, especially physiology, pathophysiology and human genetics.
Learning outcomes
After completion of the course student: understands elementary cellular processes and processes taking place during development of a human body; comprehends the complexity of intercellular communication and mutual regulation of individual cells in a multicellular organism; knows basic principles of bacterial and viral diseases; is able to express basic coherence between malfunction in cellular processes and development of diseases, especially hereditary diseases, cancers or developmental defects, and understands the principle of genetic determination of hereditary diseases; can explain and justify action of some therapeutics with emphasis on modern medicine. Student is also able to apply this knowledge and skills in other subject, especially physiology, pathophysiology and human genetics.
Syllabus
  • 1. week:
  • DNA damage and repair – from molecular mechanisms to clinical significance (doc. Mgr. Lumír Krejčí, Ph.D.)
  • 2. week:
  • Introduction to cancer biology (Mgr. Stjepan Uldrijan, CSc.)
  • 3. week:
  • Oncogenes and oncoviruses in cancer transformation (Mgr. Stjepan Uldrijan, CSc.)
  • 4. week:
  • Tumour suppressor genes and their significance for diagnostics and therapy (Mgr. Stjepan Uldrijan, CSc.)
  • 5. week:
  • Paradigm of cancer stem cells and implications for anti-cancer therapies (doc. MUDr. Iva Slaninová, Ph.D.)
  • 6. týden:
  • Gene therapy – targets and strategies of molecular therapies (doc. MUDr. Iva Slaninová, Ph.D.)
  • 7. week:
  • Stem cells and tissue engineering – prospects of regenerative medicine (prof. Ing. Petr Dvořák, CSc.)
  • 8. week:
  • From a single cell to human I – introduction to developmental biology (Mgr. Vladimír Rotrekl, Ph.D.)
  • 9. week:
  • From a single cell to human II – molecular basis of mammalian development in health and disease (Mgr. Pavel Krejčí, Ph.D.)
  • 10. week:
  • Human genome and genomics in current biomedicine (prof. MUDr. David Šmajs, Ph.D.)
  • 11. week:
  • Human microbiome (prof. MUDr. David Šmajs, Ph.D.)
  • 12. week:
  • Bioinformatics in medicine – from molecules to populations (Mgr. Vladimír Rotrekl, Ph.D.)
  • 13. week:
  • Modern approaches in studying macromolecules and their use in current biomedicine (Mgr. Vladimír Rotrekl, Ph.D.)
  • 14. week:
  • Substitution lecture
Literature
    required literature
  • ALBERTS, Bruce. Základy buněčné biologie : úvod do molekulární biologie buňky. Translated by Arnošt Kotyk. 2. vyd. Ústí nad Labem: Espero Publishing, 2004, xxvi, 630. ISBN 8090290620. info
  • PRITCHARD, D. J. and Bruce R. KORF. Základy lékařské genetiky. první české vydání. Praha: Galén, 2007, 182 stran. ISBN 9788072624492. info
    recommended literature
  • HARDIN, Jeff, Gregory BERTONI and Lewis J. KLEINSMITH. Becker's world of the cell. 8th ed. Boston: Benjamin Cummings, 2012, xxviii, 79. ISBN 9780321709783. info
  • LODISH, Harvey F. Molecular cell biology. 6th ed. New York, N.Y.: W.H. Freeman and Company, 2008, xxxvii, 11. ISBN 9780716776017. info
  • SNUSTAD, D. Peter, Michael J. SIMMONS, Jiřina RELICHOVÁ, Jiří DOŠKAŘ, Jiří FAJKUS, Petr HOŘÍN, Aleš KNOLL, Petr KUGLÍK, Jan ŠMARDA, Jana ŠMARDOVÁ, Renata VESELSKÁ and Boris VYSKOT. Genetika (Principles of Genetics). 1st ed. Brno: Masarykova univerzita, 2009, 894 pp. Učebnice. ISBN 978-80-210-4852-2. URL info
  • WEINBERG, Robert A. The biology of cancer. Second edition. London: Garland Science, 2013, xx, 876. ISBN 9780815345282. info
  • WOLPERT, L. Principles of development. 2nd ed. Oxford: Oxford University Press, 2002, xxv, 542. ISBN 0198792913. info
    not specified
  • CAMPBELL, Neil A. Biologie. Edited by Jane B. Reece. Vyd. 1. Brno: Computer Press, 2006, xxxiv, 133. ISBN 8025111784. info
Teaching methods
lecture
Assessment methods
The course Biology II builds on knowledge gained from subjects Biology I - lecture (aVLBI0121p) and Biology - seminar (aVLBI0121s). The course is completed with a written examination test taken on computers. It contains questions based on the topics discussed in the lectures, seminars and practices. The students are expected to be able to solve given problems on their own, and to derive the solutions by their own consideration based on the theory discussed in the course of both semesters and supplemented by the recommended reading.
Language of instruction
Czech
Follow-Up Courses
Further comments (probably available only in Czech)
Study Materials
The course is taught annually.
Listed among pre-requisites of other courses

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Teacher's information
https://is.muni.cz/auth/el/1411/jaro2017/VLBI0222p/index.qwarp
The course is also listed under the following terms Spring 2016, Spring 2018, spring 2019, spring 2020, spring 2021, spring 2022, spring 2023, spring 2024, spring 2025.
  • Enrolment Statistics (Spring 2017, recent)
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