LF:VLIM051p Immunology - lecture - Course Information
VLIM051p Immunology - lecture
Faculty of MedicineAutumn 2017
- Extent and Intensity
- 1/0/0. 3 credit(s). Type of Completion: zk (examination).
- Teacher(s)
- prof. MUDr. Jiří Litzman, CSc. (lecturer)
prof. MUDr. Jindřich Lokaj, CSc. (lecturer) - Guaranteed by
- prof. MUDr. Jiří Litzman, CSc.
Department of Clinical Immunology and Allergology – Institutions shared with St. Anne's Faculty Hospital – Faculty of Medicine
Contact Person: prof. MUDr. Jiří Litzman, CSc.
Supplier department: Department of Clinical Immunology and Allergology – Institutions shared with St. Anne's Faculty Hospital – Faculty of Medicine - Timetable
- Mon 18. 9. to Fri 10. 11. Mon 14:00–15:40 I.CHK N01001
- Prerequisites (in Czech)
- ( VLBC0422p Biochemistry I -lect. || VSBC0221p Biochemistry I -lect. ) && ( VSFY0422p Physiology II - lecture || VLFY0422p Physiology II - lecture )
- Course Enrolment Limitations
- The course is only offered to the students of the study fields the course is directly associated with.
- fields of study / plans the course is directly associated with
- General Medicine (programme LF, M-VL)
- Course objectives
- The course covers basic aspects of the structure and function of the immune system in humans. Topics include mechanisms of non- specific immunity with main emphasis on the inflammatory process, such as humoral and cellular branches of the specific immune response. It includes mainly mechanisms of activation of the immune response and its regulation. Special emphasis is given to immune response to microbes and immunoprophylaxis to infectious and non-infectious diseases. After finishing the course the students will understand and be able to explain the mechanisms of the immune response in physiology, such as immune system disturbances leading to immunopathological diseases.
- Learning outcomes
- - Student will understand basic mechanisms of functioning of the immune system, functional characteristics of specific and non-specific immune response, and the interrelationship of these reactions;
- The student will understand the importance of the immune system in defense against microbes and tumor growth as well as the principles of active and passive artificial immunization;
- The student will become acquainted with the regional specificity of the individual compartments of the immune system;
- Student will be acquaint with the mechanisms of immune tolerance and the mechanisms of its breakdown leading to autoimmune diseases;
- The student will be familiar with the principles of immunological hypersensitivity and the consequences leading to the development of hypersensitivity reactions;
- Students will be acquainted with basic principles of pharmacological influence of immune reactivity;
- Students will be acquainted with the most important primary and secondary immunodeficiecy states; - Syllabus
- Immunology in medicine. Medical subject allergology and clinical immunology. Physiology and pathology of the immune system.
- Immunological concept of “own”, “foreign”, “dangerous”.
- Anatomy and cellular elements of the immune system.
- Innate or natural immunity: phagocytosis, NK cells, cytotoxicity, interferon system, complement system, acute phase reaction, inflammation.
- B lymphocytes and immunoglobulins.Genetic basis of immunoglobulin heterogeneity.Biological properties of antibodies.
- T-lymphocytes, their development and effector functions. Polarisation of T-lymphocytes (T1, T2, Th17). Cytotoxicity. Cytokines. Major histocompatibility complex: structure, function.
- Activation of T and B cells by antigen.Interactions between antigen-presenting cells and T- and B-lymphocytes.
- Regulation of the immune reaction.
- Compartmentalization of the immune response. Mucosal immunity.
- Immunity against infectious agents. Microbial antigens.
- Active and passive immunisation.
- Age factor and immune system in humans
- Literature
- recommended literature
- HOŘEJŠÍ, Václav, Jiřina BARTŮŇKOVÁ, Tomáš BRDIČKA and Radek ŠPÍŠEK. Základy imunologie. 6., aktualizované vydání. V Praze: Stanislav Juhaňák - Triton, 2017, 297 stran. ISBN 9788075532503. info
- ABBAS, Abul K., Andrew H. LICHTMAN and Shiv PILLAI. Basic immunology : functions and disorders of the immune system. Fifth edition. St. Louis: Elsevier, 2016, x, 335. ISBN 9780323390828. info
- Teaching methods
- The subject is given in a form of lectures
- Assessment methods
- Oral exam.
- Language of instruction
- Czech
- Further comments (probably available only in Czech)
- Study Materials
The course can also be completed outside the examination period.
The course is taught annually. - Listed among pre-requisites of other courses
- aVLAG08 Allergology
aVLIM051p ||VLIM051p - BMBS051 Biostatistics - basic course
VLLM0522p && VLIM051p && (VSBC041p || VSBC0422p || VLBC0422p) && (VSIP0622c || VLLP0633c) - VLDV7X1c Dermatovenerology I - practice
VLPF0622p && VLPA0622p && VLLM0522p && VLIM051p && VLLP0633c - VLDV7X1p Dermatovenerology I - lecture
VLPF0622p && VLPA0622p && VLLM0522p && VLIM051p && VLLP0633c - VLIA081 Clinical Imunology and Alergology
VLIM051p && (VSPF0622c || VLPF0622c) && (VSPA0622c || VLPA0622c) - VLIN7X21c Infectious diseases - practice
VLPF0622p && VLPA0622p && VLLP0633c && VLLM0522p && VLIM051p - VLKG7X1c Clinical Genetics - practice
VLLM0522p && VLIM051p && VLLP0633c && VLPA0622p - VLKG7X1p Clinical Genetics - lecture
VLLM0522p && VLIM051p && VLLP0633c && VLPA0622p - VLOL7X1 Ophthalmology - lecture
VLPF0622p && VLPA0622p && VLLP0633c && VLLM0522p && VLIM051p
- aVLAG08 Allergology
- Enrolment Statistics (Autumn 2017, recent)
- Permalink: https://is.muni.cz/course/med/autumn2017/VLIM051p