ZLIM051p Immunology in Dentistry - lecture

Faculty of Medicine
Autumn 2016
Extent and Intensity
1/0/0. 2 credit(s). Type of Completion: zk (examination).
Teacher(s)
prof. MUDr. Vojtěch Thon, Ph.D. (lecturer)
prof. MUDr. Jiří Litzman, CSc. (lecturer)
prof. MUDr. Jindřich Lokaj, CSc. (lecturer)
Miroslava Bučková (assistant)
Guaranteed by
prof. MUDr. Vojtěch Thon, Ph.D.
Department of Clinical Immunology and Allergology – Institutions shared with St. Anne's Faculty Hospital – Faculty of Medicine
Contact Person: prof. MUDr. Vojtěch Thon, Ph.D.
Supplier department: Department of Clinical Immunology and Allergology – Institutions shared with St. Anne's Faculty Hospital – Faculty of Medicine
Timetable
Mon 7. 11. to Fri 6. 1. Tue 13:20–15:00 I.CHK N01001
Prerequisites (in Czech)
ZLBC0221p Biochemistry I - lecture && ZLFY0422c Physiology II - practice && ZLFY0422s Physiology II - seminar && ZLLM0421c Med.Oral Microbiol.I-pract. && ZC041 Handling chemical substances
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The course covers basic aspects of the structure and function of the immune system in humans. Topics include mechanisms of non- specific immunity with main emphasis on the inflammatory process, such as humoral and cellular branches of the specific immune response. It includes mainly mechanisms of activation of the immune response and its regulation. Special emphasis is given to mucosal immunity and immune response to microbes and immunoprophylaxis to infectious and non-infectious diseases in the orofacial area. After finishing the course the students will understand the mechanisms of the immune response in physiology, and the knowledge will enable them to understand the immune system disturbances leading to immunopathological diseases.
Syllabus
  • Immunology in medicine. Medical subject allergology and clinical immunology. Physiology and pathology of the immune system. Immunological concept of “own”, “foreign”, “dangerous”. Anatomy and cellular elements of the immune system. Immune mechanisms. Innate and acquired immunity. Innate or natural immunity: phagocytosis, NK cells, cytotoxicity, interferon system, complement system, acute phase reaction, inflammation. B lymphocytes and immunoglobulins. Genetic basis of immunoglobulin heterogeneity. Biological properties of antibodies. Monoclonal antibodies as diagnostic and therapeutic tools. T-lymphocytes, their development and effector functions. Polarisation of T-lymphocytes (Th1, Th2, Th17). Cytotoxicity. Cytokines. Major histocompatibility complex: structure, function. Activation of T and B cells by antigen. Interactions between antigen-presenting cells and T- and B-lymphocytes. Regulation of the immune reaction. Mucosal immunity. Immunity against infectious agents. Microbial antigens. Active and passive immunisation.
Literature
  • HOŘEJŠÍ, Václav and Jiřina BARTŮŇKOVÁ. Základy imunologie. 4. vyd. Praha: Triton, 2009, 316 s. ISBN 9788073872809. info
  • Abbas, Abul - Lichtman, Andrew. Basic Immunology. Philadelphia: Saunders, 2006. 336 s, ISBN: 1416029745
  • Imunológia :základné termíny a definície. Edited by Miroslav Ferenčík - Jozef Rovenský - Štefan Nyulassy. 2. preprac. a dopl. vyd. Bratislava: Slovac Academic Press, 2001, 348 s. ISBN 80-88908-77-9. info
Teaching methods
Lecture. To get the creditactive participation in discussions is required. The knowledge is continuously checked by oral questions.
Assessment methods
The subject is given in a form of lectures and is finihed by the exam. A credit from the subject ZLIM051c is required for the exam.
Language of instruction
Czech
Further comments (probably available only in Czech)
The course is taught annually.
Listed among pre-requisites of other courses
The course is also listed under the following terms Autumn 2006, Autumn 2007, Autumn 2008, Autumn 2009, Autumn 2010, Autumn 2011, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2015, Autumn 2017, autumn 2018, autumn 2019, autumn 2020, autumn 2021, autumn 2022, autumn 2023, autumn 2024.
  • Enrolment Statistics (Autumn 2016, recent)
  • Permalink: https://is.muni.cz/course/med/autumn2016/ZLIM051p