LF:VSBC0221p Biochemistry I -lect. - Course Information
VSBC0221p Biochemistry I - lecture
Faculty of MedicineSpring 2007
- Extent and Intensity
- 2/0. 4 credit(s). Type of Completion: zk (examination).
- Teacher(s)
- doc. RNDr. Jiří Dostál, CSc. (lecturer)
prof. MUDr. Vladimír Palyza, CSc. (lecturer)
doc. MUDr. Jaromír Sláma, CSc. (lecturer)
prof. RNDr. Eva Táborská, CSc. (lecturer)
doc. RNDr. Jaroslava Tallová, CSc. (lecturer)
Lenka Nerudová (assistant)
Mgr. Jiří Slanina, Ph.D. (assistant)
doc. RNDr. Josef Tomandl, Ph.D. (assistant) - Guaranteed by
- prof. RNDr. Eva Táborská, CSc.
Department of Biochemistry – Theoretical Departments – Faculty of Medicine - Timetable of Seminar Groups
- VSBC0221p/01: Wed 9:30–11:20 P31 Posluchárna A. I. Bláhy
VSBC0221p/02: Wed 7:30–9:20 P51 Posluchárna V. Čermáka - Prerequisites (in Czech)
- VSLC011s Med.Chem.-seminar && VSLC011c Medical Chemistry -p
- Course Enrolment Limitations
- The course is only offered to the students of the study fields the course is directly associated with.
- fields of study / plans the course is directly associated with
- there are 6 fields of study the course is directly associated with, display
- Syllabus
- Enzymes. Characteristic features of biocatalysis, enzyme structure and function, nomenclature and classification of enzymes. Enzyme cofactors, review of structures and functions. Mechanisms of enzyme action. Kinetics of enzyme catalyzed reactions. Assays of enzyme activity, the conditions used. Factors affecting catalytic activity of enzymes, types of enzyme inhibition. Metabolism: basic concepts and design. Biological oxidations, generation of high-energy compounds. Saccharide metabolism: the glycolytic pathway and aerobic decarboxylation of pyruvate. Gluconeogenesis. Glycogen biosynthesis and breakdown. The pentose phosphate pathway. The glucuronate pathway. Interconversions of monosaccharides and of their derivatives. Protein and amino acid metabolism. The common reactions in amino acid degradation. The ureosynthetic cycle. Metabolic breakdown of individual amino acids. Biosynthesis and breakdown of fatty acids, ketogenesis. Synthesis of triacylglycerols. Metabolism of phospholipids and glycolipids. Synthesis of eicosanoids. Biosynthesis and transformations of cholesterol, biosynthesis of bile acids. Interrelationships among the major pathways involved in energy metabolism. The citric acid cycle. Synthesis of haem. Mitochondria. Oxidative phosphorylation - mitochondrial electron transport chain, synthesis of ATP. Biosynthesis and catabolism of purine and pyrimidine nucleotides. Chromatin, DNA replication. DNA transcription. Regulation of gene expression. Protein synthesis and post-translational processing.
- Literature
- LEDVINA, Miroslav, Alena STOKLASOVÁ and Jaroslav CERMAN. Biochemie pro studující medicíny (I. a II. díl). 1st ed. Praha: Karolinum, 2004, 561 pp. ISBN 80-246-0851-0. info
- MURRAY, R.K. and D.K. GRANNER. Harperova biochemie. 3. v ČR. Jinočany: H & H, 2001, 872 pp. ISBN 80-7319-003-6. info
- HOLEČEK, Milan. Regulace metabolizmu cukrů, tuků, bílkovin a aminokyselin. 1st ed. Praha: Grada Publishing, 2006, 286 pp. učebnice. ISBN 80-247-1562-7. info
- Biochemistry :a concise text for medical students. Edited by D. K. Apps. 5th ed. London: Bailliere Tindall, 1992, vii, 448 s. ISBN 0-7020-1444-3. info
- MURRAY, R. K., D. K. GRANNER and V. W. RODWELL. Harper's Illustrated Biochemistry. 27th ed. New York: Lange, 2006, 692 pp. textbook. ISBN 0-07-147885-x. info
- CHAMPE, P. C., R. A. HARVEY and D. R. FERRIER. Lippincott's Illustrated Reviews: Biochemistry. 3rd ed. Philadelphia: Lippincott Williams & Wilkins, 2005, 534 pp. textbook. ISBN 0-7817-2265-9. info
- Language of instruction
- Czech
- Further comments (probably available only in Czech)
- Information on completion of the course: zkoušku lze konat až po absolvování zkoušky z Lékařské chemie
The course is taught annually.
Information on course enrolment limitations: Přihlášení ke zkoušce je podmíněno vykonáním zkoušky z Lékařské chemie. - Listed among pre-requisites of other courses
- BVTO0311c Medical toxicology - laboratory course
BVBC0221p||VSBC0221p&&BVEK011p - BVTO0311p Medical toxicology - lecture
BVBC0221p||VSBC0221p&&BVEK011p - VLIM051c Immunology - practice
(VLBC0422p ||VSBC0221p) && (VSFY0422p || VLFY0422p) - VLIM051p Immunology - lecture
(VLBC0422p ||VSBC0221p) && (VSFY0422p || VLFY0422p)
- BVTO0311c Medical toxicology - laboratory course
- Teacher's information
- http://www.med.muni.cz/toCP1250.cs/biochem/vyuka.html
- Enrolment Statistics (Spring 2007, recent)
- Permalink: https://is.muni.cz/course/med/spring2007/VSBC0221p