AMOLp Introduction into molecular biology and genetics

Faculty of Medicine
Spring 2011
Extent and Intensity
2/2/0. 3 credit(s). Type of Completion: zk (examination).
Teacher(s)
prof. Ing. Petr Dvořák, CSc. (lecturer)
Mgr. Vladimír Rotrekl, Ph.D. (lecturer)
prof. MUDr. Augustin Svoboda, CSc., dr. h.c. (lecturer)
prof. MUDr. David Šmajs, Ph.D. (lecturer)
Mgr. Stjepan Uldrijan, CSc. (lecturer)
Mgr. Hana Hříbková, Ph.D. (assistant)
Debora Ledahudcová (assistant)
Mgr. Lenka Paštěková, Ph.D. (assistant)
Ing. Lucia Ráheľová (assistant)
Eva Skalová (assistant)
Mgr. Kateřina Vopěnková, Ph.D. (assistant)
Mgr. Martina Vráblíková (assistant)
Guaranteed by
prof. Ing. Petr Dvořák, CSc.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: Mgr. Hana Hříbková, Ph.D.
Timetable
Tue 11:10–12:50 B11/334
Prerequisites
Grammar school or similar type with biology education
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
The subject provides a survey of basic knowledge from molecular and cell biology as well as from human genetics. Selected topics in molecular and cell biology include storage and expression of genetic information, cell structure and function including cellular interactions, development, basic genetics. The above mentioned knowledge is a prerequisite of further theoretic and preclinical studies.
Syllabus
  • Cellular organization of living systems. Biopolymers. Cell memory. Genetic information. DNA replication. Expression of genetic information and its regulation. Translation and protein metabolism. Biomembranes and energy transformation. Membrane transport. Organization of cell nucleus.Cytoskeleton. Motor proteins. Cell cycle and its control. Mitosis and cytokinesis. Cell interactions and signalling. Stem cells and strategy of cell therapy. Cell differentiation. Neoplastic transformation of cells. From gene to trait: Mendel rules of heredity. Hereditary diseases. Genetic counselling. Human genome. Gene cloning. Genetic engineering. Molecular disgnostics of hereditary diseases. Gene therapy.
Literature
  • Další literatura ke studiu: Neil A. Campbell a Jane B. Reece: BIOLOGIE. Český překlad 6. angl. vydání Computer Press, Brno 2006, 1332 stran ISBN: 80-251-1178-4
  • NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
  • ALBERTS, Bruce. Základy buněčné biologie :úvod do molekulární biologie buňky. 1. vyd. Ústí nad Labem: Espero, 1999, xxvi, 630. ISBN 80-902906-0-4. info
Teaching methods
two-hour lecture per week
Assessment methods
written and oral examination, lecture attendance is mandatory
Language of instruction
Czech
Further Comments
Study Materials
The course is taught annually.
The course is also listed under the following terms Spring 2008, Spring 2009, Spring 2010, Spring 2012, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, Spring 2018, spring 2019, spring 2020, spring 2021, spring 2022, spring 2023, spring 2024, spring 2025.
  • Enrolment Statistics (Spring 2011, recent)
  • Permalink: https://is.muni.cz/course/med/spring2011/AMOLp