AMOLp Introduction into molecular biology and genetics - lecture

Faculty of Medicine
Spring 2014
Extent and Intensity
2/0. 3 credit(s). Type of Completion: zk (examination).
Teacher(s)
prof. Ing. Petr Dvořák, CSc. (lecturer)
Mgr. Vladimír Rotrekl, Ph.D. (lecturer)
prof. MUDr. Augustin Svoboda, CSc., dr. h.c. (lecturer)
prof. MUDr. David Šmajs, Ph.D. (lecturer)
Mgr. Stjepan Uldrijan, CSc. (lecturer)
Mgr. Hana Hříbková, Ph.D. (seminar tutor)
Mgr. Kateřina Vopěnková, Ph.D. (seminar tutor)
Jana Růžičková (assistant)
Eva Skalová (assistant)
Mgr. Martina Vráblíková (assistant)
Guaranteed by
prof. Ing. Petr Dvořák, CSc.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: Mgr. Kateřina Vopěnková, Ph.D.
Supplier department: Department of Biology – Theoretical Departments – Faculty of Medicine
Timetable
Tue 11:10–12:50 B11/334
Prerequisites
(! VSBI0222p Biology II -lect. ) && (! ZLBI0222p Biology II-lect. ) && (! PřF:Bi1700 Cell Biology )
Grammar school or similar school type with biology education
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
After completion of the course student: understands elementary cellular processes; comprehends the complexity of intercellular communication and mutual regulation of individual cells in a multicellular organism; is able to explain the difference between healthy and pathologically-working cell; is able to express basic coherence between malfunction in cellular processes and development of diseases, especially hereditary diseases, cancers or developmental defects. Student is also able to apply this knowledge and skills in following subjects.
Syllabus
  • Cellular organization of living systems. Biopolymers.
  • Cell memory. Preservation and duplication of genetic information.
  • Expression of genetic information and its regulation.
  • Translation and protein metabolism.
  • Biomembranes and energy transformation. Membrane transport.
  • Organization of cell nucleus. Chromosomes.
  • Cytoskeleton. Motor proteins.
  • Cell cycle. Mitosis.
  • Cell interactions and signalling. Secretion pathway and endocytosis.
  • Stem cells and strategy of cellular therapy.
  • Neoplastic transformation of cells. Intracellular signal transduction.
  • From gene to trait: Mendelian genetics.
  • Mechanisms of DNA repair and genome stability. Mutations and hereditary diseases.
  • Genetic engineering. Human genome. Molecular disgnostics. Gene therapy.
Literature
    recommended literature
  • NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
  • CAMPBELL, Neil A. Biologie. Edited by Jane B. Reece. Vyd. 1. Brno: Computer Press, 2006, xxxiv, 133. ISBN 8025111784. info
  • ALBERTS, Bruce. Základy buněčné biologie : úvod do molekulární biologie buňky. Translated by Arnošt Kotyk. 2. vyd. Ústí nad Labem: Espero Publishing, 2004, xxvi, 630. ISBN 8090290620. info
Teaching methods
two-hour lecture per week
Assessment methods
Lectures attendance is optional. The course is completed with a written multiple choice exam test containing 45 questions with 4 possible answers. The test is based on knowledge of all topics from lectures and practices (succesfull practice passing is required for the exam). Student chooses all correct answers (minimum 1, maximum 4), negative marking is obtained for incorrect answers. Maximum points: 45; points needed for successful exam passing: 20. More information on the exam: https://is.muni.cz/auth/el/1411/jaro2014/AMOLp/op/Pokyny_ke_zkousce_AMOL.pdf Requirements for attendance at the exam: successful passing of the subject’s practice.
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
The course is taught annually.
Information on course enrolment limitations: Student nesmí mít absolvovaný ani současně zapsaný předmět Biologie II na LF, ani předmět Bunečná biologie Bi1700 na PřF.
The course is also listed under the following terms Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, Spring 2013, Spring 2015, Spring 2016, Spring 2017, Spring 2018, spring 2019, spring 2020, spring 2021, spring 2022, spring 2023, spring 2024, spring 2025.
  • Enrolment Statistics (Spring 2014, recent)
  • Permalink: https://is.muni.cz/course/med/spring2014/AMOLp