EMBI0222s Biologie II - seminář

Faculty of Medicine
spring 2022
Extent and Intensity
0/1/0. 4 credit(s). Type of Completion: zk (examination).
Teacher(s)
prof. MUDr. Iva Slaninová, Ph.D. (lecturer)
prof. RNDr. Ondřej Slabý, Ph.D. (lecturer)
prof. MUDr. David Šmajs, Ph.D. (lecturer)
Mgr. Stjepan Uldrijan, CSc. (lecturer)
Mgr. Vladimír Rotrekl, Ph.D. (lecturer)
Mgr. Kateřina Cetkovská, Ph.D. (assistant)
Ing. Lívia Eiselleová, Ph.D. (assistant)
Mgr. Kateřina Francová, Ph.D. (assistant)
Jana Růžičková (assistant)
Guaranteed by
prof. MUDr. Iva Slaninová, Ph.D.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: Mgr. Kateřina Francová, Ph.D.
Supplier department: Department of Biology – Theoretical Departments – Faculty of Medicine
Timetable
Wed 16. 2. 13:00–13:50 B11/234, Wed 23. 2. 13:00–13:50 B11/234, Wed 2. 3. 13:00–13:50 B11/234, Wed 9. 3. 13:00–13:50 B11/234, Wed 16. 3. 13:00–13:50 B11/234, Wed 23. 3. 13:00–13:50 B11/234, Wed 30. 3. 13:00–13:50 B11/234, Wed 6. 4. 13:00–13:50 B11/234, Wed 13. 4. 13:00–13:50 B11/234, Wed 20. 4. 13:00–13:50 B11/234, Wed 27. 4. 13:00–13:50 B11/234, Wed 4. 5. 13:00–13:50 B11/234, Wed 11. 5. 13:00–13:50 B11/234, Wed 18. 5. 13:00–13:50 B11/234
Prerequisites
EMBI0121s Biologie I - seminář
Knowledge of high-school biology and all previous lectures of the course are prerequisites for studying the course. Expected knowledge for each lecture is specified in the course syllabus. The literature recommended for studying before each lecture is detailed in the interactive syllabus of the course.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The main objectives of the course are:
- understanding of the basic principles of human genetics
- understanding of the mechanisms of cancer development
- acquaintance with the basics of genomics, immunogenetics, epigenetics, gene therapy, tissue engineering and evolutionary biology
Learning outcomes
After completing the course, the student will be able to:
- explain and apply basic principles of human genetics
- explain the role of medical biology in the development of modern therapies (e.g. molecular therapies of cancer)
- explain the basic principles of current methods used in gene therapy and cell therapies
- understand the significance of the human microbiome in human health and disease
- be knowledgeable in basic modern approaches to studying various diseases and to personalised medicine (genomics)
Syllabus
  • Introduction to Genetics I – Genetics in Medicine, Mendelian Inheritance, Autosomal and Gonosomal Inheritance, Chromosome Abnormalities
  • Introduction to Genetics II – Multifactorial Inheritance, Genetic Linkage, Population Genetics
  • Human genome and methods of its study
  • Epigenetics – Interaction of Genes and Environment
  • Immunogenetics
  • Cancer Biology I – Carcinogenesis, Hallmarks of Cancer
  • Cancer Biology II – Oncogenes and tumour suppressors, oncogenic viruses
  • Bacterial and Viral Genomics
  • Use of knowledge of molecular biology and genetics in medicine
  • Gene Therapy
  • Human Microbiome
  • Stem Cells and Tissue Engineering
  • Evolutionary Biology
Literature
    required literature
  • PRITCHARD, D. J. and Bruce R. KORF. Základy lékařské genetiky. první české vydání. Praha: Galén, 2007, 182 stran. ISBN 9788072624492. info
  • ALBERTS, Bruce. Základy buněčné biologie : úvod do molekulární biologie buňky. Translated by Arnošt Kotyk. 2. vyd. Ústí nad Labem: Espero Publishing, 2004, xxvi, 630. ISBN 8090290620. info
    not specified
  • ALBERTS, Bruce. Essential cell biology. 4th edition. New York, N.Y.: Garland Science, 2014, xxiii, 726. ISBN 9780815344551. info
  • Medical genetics at a glance. Edited by D. J. Pritchard - Bruce R. Korf. 3rd ed. Chichester, England: Wiley-Blackwell, 2013, 1 online r. ISBN 9781118689028. info
Teaching methods
seminar every week
Assessment methods
The course of Biology II builds on the knowledge gained from Biology I, and is completed with a written examination test. The test contains questions based on the topics discussed in the lectures of both semesters. The students are expected to be able to autonomously solve assigned problems and to derive the solutions using their own thinking – based on the theory discussed during both semesters and supplemented by the recommended reading. The test contains 60 questions in total. Information about test will be specified.
Language of instruction
Czech
Further comments (probably available only in Czech)
Information on the extent and intensity of the course: 15.
Listed among pre-requisites of other courses
Teacher's information
https://is.muni.cz/auth/el/med/jaro2022/EMBI0222s/index-ebtzDw.qwarp
Seminars take place every week and are compulsory. We recommend to follow the Interactive syllabus of the course where students can find all relevant information (schedule, substitutions, public holidays etc.), and also corresponding study literature for each week, and links to animations and videos relevant to the topic. https://is.muni.cz/auth/el/med/jaro2022/EMBI0222s/index-ebtzDw.qwarp
  • Enrolment Statistics (recent)
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