AMOLp Introduction into molecular biology and genetics

Faculty of Medicine
Spring 2013
Extent and Intensity
2/2/0. 3 credit(s). Type of Completion: zk (examination).
Teacher(s)
prof. Ing. Petr Dvořák, CSc. (lecturer)
Mgr. Vladimír Rotrekl, Ph.D. (lecturer)
prof. MUDr. Augustin Svoboda, CSc., dr. h.c. (lecturer)
prof. MUDr. David Šmajs, Ph.D. (lecturer)
Mgr. Stjepan Uldrijan, CSc. (lecturer)
Mgr. Hana Hříbková, Ph.D. (seminar tutor)
Mgr. Kateřina Vopěnková, Ph.D. (seminar tutor)
Eva Skalová (assistant)
Mgr. Martina Vráblíková (assistant)
Guaranteed by
prof. Ing. Petr Dvořák, CSc.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: Mgr. Kateřina Vopěnková, Ph.D.
Supplier department: Department of Biology – Theoretical Departments – Faculty of Medicine
Timetable
Tue 11:10–12:50 B11/334
Prerequisites
Grammar school or similar school type with biology education
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The subject provides basic knowledge of molecular and cell biology and human genetics, including cell structure and function, preservation and expression of genetic information, cellular interactions and metabolism, development, basics of cancer biology and basic genetics. This knowledge is a prerequisite for further theoretical and preclinical studies.
Syllabus
  • Cellular organization of living systems. Biopolymers. Cell memory. Presrvation and duplication of fenetic information. Expression of genetic information and its regulation. Translation and protein metabolism. Biomembranes and energy transformation. Membrane transport. Organization of cell nucleus. Chromosomes. Cytoskeleton. Motor proteins. Cell cycle. Mitosis and cytokinesis. Cell interactions and signalling. Secretion pathway and endocytosis. Stem cells and strategy of cellular therapy. Neoplastic transformation of cells. Intracellular signal transduction. From gene to trait: Mendelian genetics. Mechanisms of DNA repair and genome stability. Mutations and hereditary diseases. Genetic engineering. Human genome. Molecular disgnostics. Gene therapy.
Literature
    recommended literature
  • NEČAS, Oldřich, Augustin SVOBODA, Milan HEJTMÁNEK, Roman JANISCH, Miroslav ČERVINKA, Karel LENHART and Zdeněk KOLÁŘ. Obecná biologie pro lékařské fakulty (General Biology for Medical Faculties). 3. přepracované, v H+H 1. Jinočany: H+H, 2000, 554 pp. ISBN 80-86022-46-3. info
  • CAMPBELL, Neil A. Biologie. Edited by Jane B. Reece. Vyd. 1. Brno: Computer Press, 2006, xxxiv, 133. ISBN 8025111784. info
  • ALBERTS, Bruce. Základy buněčné biologie : úvod do molekulární biologie buňky. Translated by Arnošt Kotyk. 2. vyd. Ústí nad Labem: Espero Publishing, 2004, xxvi, 630. ISBN 8090290620. info
Teaching methods
two-hour lecture per week
Assessment methods
Written exam of multiple choice type. The test contains 45 questions generated out of 15 syllabus chapters. The test is evaluated electronically and the results are transferred to the IS. Maximal number of points is 45. For successful exam passing 20 points are needed.
Language of instruction
Czech
Further Comments
Study Materials
The course is taught annually.
The course is also listed under the following terms Spring 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, Spring 2014, Spring 2015, Spring 2016, Spring 2017, Spring 2018, spring 2019, spring 2020, spring 2021, spring 2022, spring 2023, spring 2024, spring 2025.
  • Enrolment Statistics (Spring 2013, recent)
  • Permalink: https://is.muni.cz/course/med/spring2013/AMOLp