PřF:Bi4020 Molecular biology - Course Information
Bi4020 Molecular biology
Faculty of ScienceSpring 2010
- Extent and Intensity
- 3/0/0. 3 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
- Teacher(s)
- prof. RNDr. Jiří Doškař, CSc. (lecturer)
- Guaranteed by
- prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: prof. RNDr. Jiří Doškař, CSc. - Timetable
- Tue 13:00–15:50 aula_Vinařská
- Prerequisites
- ! Bi4010 Essential molecular biology
Basic knowledge of general zoology and botany, microbiology, genetics, physiology, organic chemistry and biochemistry. - Course Enrolment Limitations
- The course is also offered to the students of the fields other than those the course is directly associated with.
- fields of study / plans the course is directly associated with
- there are 20 fields of study the course is directly associated with, display
- Course objectives
- At the end of the course students should be able to understand and expain basic principles of molecular biology and genetics on molecular level and their basic phenomena - the structure, replication, expression and changes of genes.
- Syllabus
- History of molecular biology
- Nucleic acids (primary, secondary and tertiary structure of DNA and RNA, different conformations of DNA and their significance in biological systems)
- Interactions of proteins with DNA
- Genetic information and the genetic code. Molecular structure of procaryotic and eucaryotic genome. Replication of procaryotic and eucaryotic genome
- Transcription of procaryotic and eucaryotic genome
- Postranscriptional modification and processing of RNA, especially in eucaryotes
- Mechanisms of splicing and selfsplicing
- Translation of procaryotic and eucaryotic mRNA
- Posttranslational processing
- Regulation of gene expression in procaryotes and eucaryotes
- Signal pathways in mammal cells and their relation to the activation of transcription factors. Molecular basis of acquired immunity
- Molecular basis of cancerogenesis (oncogenes, antioncogenes
- Molecular mechanisms of mutagenesis and recombination
- Transposons
- Repair mechanisms of damaged DNA
- Basic principles of gene engineering
- Literature
- ROSYPAL, Stanislav. Úvod do molekulární biologie (Introduction to molecular biology). Čtvrté inovované vydání. Brno: Prof. RNDr. Stanislav Rosypal, DrSc., Brno, 2006, 290 pp. Díl I. Molekulární biologie prokaryotické buňky. ISBN 80-902562-5-2. URL info
- ROSYPAL, Stanislav. Úvod do molekulární biologie. Třetí inovované vydání. Brno, 1999, 300 pp. Díl II. Molekulární biologie eukaryot. ISBN 80-902562-1-X. URL info
- ROSYPAL, Stanislav. Úvod do molekulární biologie. Třetí inovované vydání. Brno, 2000, 300 pp. Díl III. Molekulární biologie virů. ISBN 80-902562-2-8. URL info
- ROSYPAL, Stanislav, Jiří DOŠKAŘ, Karel PETRZIK and Vladislava RŮŽIČKOVÁ. Úvod do molekulární biologie IV. Molekulární biologie rostlinných virů, Priony, Molekulkární evoluce, Vznik života, Metody molekulární biologie, Genové inženýrství (Introduction to molecular biology IV.). Třetí inovované vydání. Brno: Rosypal S., Grafex, 2002, 300 pp. Díl čtvrtý. ISBN 80-902562-4-4. info
- ROSYPAL, Stanislav, Jiří DOŠKAŘ, Roman PANTŮČEK, Jana KAILEROVÁ, Jiřina RELICHOVÁ, Vladislava RŮŽIČKOVÁ, Jan ŠMARDA, Jan ŠMARDA and Jiří ŠTĚPÁN. TERMINOLOGIE MOLEKULÁRNÍ BIOLOGIE. České odborné termíny, definice a anglické ekvivalenty (Terminology of molecular biology). První vydání. Brno: Vydavatel Prof. RNDr. Stanislav Rosypal, DrSc. Vodova 80, 612 00 Brno, 2001, 300 pp. ISBN 80-902562-3-6. URL info
- ALBERTS, Bruce. Základy buněčné biologie : úvod do molekulární biologie buňky a : Essential cell biology (Orig.). Ústí nad Labem: Espero Publishing, xxvi, 630,. info
- CLARK, David P. Molecular biology. Amsterdam: Elsevier, 2005, xviii, 784. ISBN 0121755517. info
- ALBERTS, Bruce. Molecular biology of the cell. 5th ed. New York, N.Y.: Garland science, 2008, xxxiii, 12. ISBN 9780815341062. info
- Teaching methods
- Lectures are based on power-point pictures, tables and texts elaborated accordindg to textbooks, monographs and scientific papers wich are explained and complemented with live commentaries. All the presentations are available on IS MUNI.
- Assessment methods
- Visiting of the course is not obligatory. The exam is a written test in which students should answer 50 questions covering main topics of individual lectures. To pass the exam the stduents should answer 60% of the answers.
- Language of instruction
- Czech
- Follow-Up Courses
- Further comments (probably available only in Czech)
- The course is taught annually.
- Listed among pre-requisites of other courses
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Bi3030 || Bi6790 && (NOW(Bi4020) || Bi4020) && !Bi1100en - Bi3001 Bachelor thesis EMB 1
Bi4020 || JA001 || JA002 || JA001A && NOW(Bi3330) || NOW(Bi3332) || NOW(Bi3334) || NOW(Bi3336) || NOW(Bi3338) - Bi4010 Essential molecular biology
!Bi4020 - Bi4010c Essential molecular biology - seminar
!Bi4020c && (NOW(Bi4010) || NOW(Bi4020) || Bi4010 || Bi4020) - Bi4020c Molecular biology - laboratory practice
(C1600 || C1080 || C1620 || C1650 || C2100 || C2500 || C2740 || C2480 || Bi9410 || souhlas) && (Bi4020 || NOW(Bi4020)) && !NOWANY(Bi4010c,Bi4035) && !Bi4010c && !Bi4035 - Bi4025en Molecular Biology
(!Bi4020) && (!Bi4010) && !NOWANY(Bi4010,Bi4020) - Bi4030c Molecular biology - practice
(Bi4020 || NOW(Bi4020)) && (Bi4030 || NOW(Bi4030)) - Bi5000 Bioinformatics
Bi4010 || Bi4020
- Bi0580 Developmetal Genetics
- Enrolment Statistics (Spring 2010, recent)
- Permalink: https://is.muni.cz/course/sci/spring2010/Bi4020